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Webinar

Change in grade and differentiation: what do we learn for patient management?

This webinar will delve into the crucial role that tumour grade and differentiation play in managing neuroendocrine tumours (NETs) and neuroendocrine carcinomas (NECs). We’ll explore key topics such as the potential transformation from NET to NEC, the implications of increasing tumour grade over time, and the importance of re-biopsy. Additionally, we’ll examine how therapeutic pressure can influence tumour progression and differentiation. Join us for an insightful session that will shed light on how these factors guide treatment choices and impact patient outcomes.

This webinar is free and open to all healthcare professionals. However, prior registration is required to attend. The Zoom registration link is now available—click the button below to register and secure your place.  

Educational Level:

Advanced

Keywords:

NET grade 3, temporal heterogeneity, therapeutic preasure, lineage plasticity, NEN progression

Downloads:

Agenda:

Moderator: Margot TESSELAAR, (NED)

18:00 – 18:05     Opening comments – Margot TESSELAAR (NED)

18:05 – 18:20     Does NET/NEC transformation exist? – Halfdan SORBYE (NOR)

18:20 – 18:35     Increased grading over time (justify re-biopsy) – Louis DE MESTIER (FRA)

18:35 – 18:50     Role of therapeutic pressure – Justo CASTAÑO (ESP)

18:50 – 19:05     Panel discussion

19:05 – 19:10    Closing comments – Margot TESSELAAR (NED)

 

Moderators:

Speakers:

The webinar series is intended for HCPs qualified by law to prescribe medicine.

 

 

Conflict of Interest Disclosure

In line with EACCME® standards, all faculty participating in this webinar have disclosed any potential conflicts of interest. The disclosures are available to all participants before and during the webinar session.

  • Margot TESSELAAR (moderator) has the following potential conflict(s) of interest to report:
    • Receipt of grants/research supports: Merck BV
  • Halfdan SORBYE (speaker) has the following potential conflict(s) of interest to report:
    • Receipt of honoraria or consultation fees: Ipsen, BMS, Pierre Fabre, Daiichi Sankyo, AAA
  • Louis DE MESTIER (speaker) has the following potential conflict(s) of interest to report:
    • Receipt of grants/research supports: Ipsen, Esteve
    • Receipt of honoraria or consultation fees: AAA/Novartis, Boehringer-Ingelheim, Esteve, Ipsen, Mayoly, Servier, Viatris
  • Justo CASTAÑO (speaker) has the following potential conflict(s) of interest to report:
    • Receipt of grants/research supports: IPSEN
    • Receipt of honoraria or consultation fees: Endocrine Oncology EiC (Bioscientifica)
    • Speaker fees or travel support: IPSEN, ADACAP (Novartis), Medscape (prIME Oncology)

 

UEMS- EACCME® Accreditation Statement

The Webinar Change in grade and differentiation: what do we learn for patient management?, Virtual, Germany 27/03/2025 - 27/03/2025, has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 1.0 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at https://edhub.ama-assn.org/pages/applications.

Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.