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#969 Identification of Hypoxia Induced Epigenetic Changes in the Development of Pancreatic Neuroendocrine Tumors

Introduction: In VHL syndrome, pancreatic NETs develop through bi-allelic inactivation of VHL with subsequent HIF pathway activation. This also occurs in sporadic pancreatic NETs.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Dibra H, Connor T, Ashcroft M, Maxwell P, Thirlwell C,

Keywords: neuroendocrine, von Hippel-Lindau (VHL), hypoxia, epigenetics,