Abstract Library

#3416 MEN1 gene sequence variant C.[527 G> A] P.[ARG 176 GLN]: Is it pathogenic?

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare syndrome with a severe impact on quality of life of patients and their relatives and early diagnosis is mandatory. Many single-nucleotide polymorphisms of the MEN1 gene are reported, but only few are pathogenic.

Conference:

Presenting Author:

Authors: Zanata I, Crociara A, Ambrosio M, Bondanelli M, Aliberti L,

Keywords: MEN1, C.[527 G> A] P.[ARG 176 GLN], sequence variant,

#479 Efficacy and Safety of Everolimus in Metastatic Gastroenteropancreatic Neuroendocrine Tumors

Introduction: Everolimus is a treatment option for patients with pancreatic NETs, while its use in patients with gastrointestinal NETs still remains to be defined.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Ambrosio M, Guerra A, Lupo S, Bondanelli M, Sartori S,

Keywords: Everolimus, GEP-NET, efficacy, side effects,

#425 Successful Treatment with Everolimus of Functioning Liver Metastases From a Pancreatic Insulinoma

Introduction: Medical treatment of metastatic insulinoma is debated.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Zatelli M, Ambrosio M, Franceschetti P, Lunardon S, Bondanelli M,

Keywords: Everolimus, insulinoma,

#265 A Novel PKCßII Inhibitor Induces Antiproliferative Effects in Human Pancreatic Neuroendocrine Tumor Cells

Introduction: Deregulation of the protein kinase C (PKC) signaling pathway has been implicated in tumor progression.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Molè D, Gagliano T, Gentilin E, Bondanelli M, Tagliati F,

Keywords: PKCßII, selective inhibitor, human pancreatic neuroendocrine cell line,