Abstract Library

#905 Cancer-Associated-Fibroblasts in Neuroendocrine Neoplasms: A Role in Cancer Progression

Introduction: Cancer-associated-fibroblasts (CAFs) secrete soluble factors that enhance tumor growth and invasion. Neuroendocrine tumor (NET) cells recruit fibroblasts within the lesional sites.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Cives M

Authors: Cives M, Simone V, Rizzo F, Bisceglia F, Vecchio M,

Keywords: CAF, microenvironment, neuroendocrine tumors ,

#757 Circulating Endothelial Cells in Neuroendocrine Tumors

Introduction: Circulating endothelial cells (CECs) are mature endothelial cells that are shed into the bloodstream. We hypothesised that neuroendocrine tumors (NETs), being highly vascular, may shed more CECs into the circulation, and that changes in their number may serve as a biomarker for anti-angiogenic therapy.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Mandair D, Khan M, Lowe H, Griffin N, Tsigani T,

Keywords: biomarker,

#180 Microvessel Density and Prognosis of Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETS)

Introduction: The role of anti-angiogenic agents in GEP-NETS remains to be established. CD105 (Endoglin) identifies the TGF-ß1 receptor which is expressed on endothelial cells involved in tumor angiogenesis.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Soares C, Bettencourt H, Preto J, Soares P, Pinto-de-Sousa J,

Keywords: gastroenteropancreatic neuroendocrine tumors, angiogenesis, microvessel density, CD105, Endoglin,