Abstract Library

#2908 Re-Cellularised Human Pancreas 3D Scaffolds as a Novel Model for Biomarker Discovery in Pancreatic Neuroendocrine Tumours (pNETs)

Introduction: The lack of preclinical models of pNETs has challenged identification of tissue specific biomarkers of disease. Culturing cancer cells in their native tissue enables the close study of cell-ECM interaction and tissue remodelling. The biological products of such interactions can form a basis for discovery of novel biomarkers of the disease, and were previously linked with a range of inflammatory and malignant conditions.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Ney A

Authors: Ney A, Al-Akkad W, Frenguelli L, Acedo P, Mazza G,

Keywords: 3d models, pancreatic neuroendocrine tumors, Biomarkers,

#1567 Pancreatic Neuroendocrine Tumors: Experience from a Single Institute

Introduction: A dedicated multidisciplinary team is necessary in the management of pancreatic neuroendocrine tumor (pNET).

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Caff A, Cordio S, Pellegriti G, Russo M, Trovato M,

Keywords: pancreatic, Ki-67,

#1550 Very Early Response to Sunitinib in VHL Patient with Pancreatic Neuroendocrine Tumor

Introduction: Pancreatic neuroendocrine tumors (pNET) arise in 8-17% of Von Hippel Lindau (VHL) patients and surgery plays a key role for resectable lesions. Alternative medical therapy, such as target therapy (TT), can be used when surgery is unfeasible

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Caff A

Authors: Caff A, Cittadini G, De Cian F, Sciallero S, Malandrino P,

Keywords: VHL therapy,

#905 Cancer-Associated-Fibroblasts in Neuroendocrine Neoplasms: A Role in Cancer Progression

Introduction: Cancer-associated-fibroblasts (CAFs) secrete soluble factors that enhance tumor growth and invasion. Neuroendocrine tumor (NET) cells recruit fibroblasts within the lesional sites.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Cives M

Authors: Cives M, Simone V, Rizzo F, Bisceglia F, Vecchio M,

Keywords: CAF, microenvironment, neuroendocrine tumors ,

#279 Coexistence of a Somatostatin-Producing Carcinoma of Duodenum and a Jejuna Gastrointestinal Stromal Tumor (GIST) in a Patient with Von Recklinghausen’s Disease

Introduction: Duodenal neuroendocrine tumors comprise 2-3% of all neuroendocrine tumors of the gastrointestinal tract. Coexistence of NF-1, NET and GIST is rare and only five cases have been described in the literature.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Daraki V, Stamou K, ?amalaki E, Spyrou F, Kalikakis G,

Keywords: somatostatinoma, Neurofibromatosis Type 1 , GIST, ,