Abstract Library

#1561 PD1 and PDL1 Expression in Midgut Neuroendocrine Tumors

Introduction: PD1/PDL1 inhibitors have shown promising results in different carcinomas, and correlation between PDL1 expression and response to immunotherapy has been reported. No studies thus far have investigated the expression of PD1 or PDL1 in midgut NETs.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Cives M, Strosberg J, Coppola D,

Keywords: midgut NETs, PD1, PD-L1, lymph node-like structures,

#1181 Significance of Ectopic Lymph Node-Like Structures in Neuroendocrine Tumors of the Small Bowel

Introduction: The formation of extranodal tertiary lymphoid follicles and lymphoid cell aggregates has been described in nonmalignant conditions including autoimmune diseases and chronic inflammation as well as in cancer. Tumor-induced lymph node-like structures (LLS) participate in the host’s antitumor immune response by driving intratumoral immune cell priming

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Cives M, Strosberg J, Simons S, Coppola D,

Keywords: Immune microenvironment,lymph node-like structures,