Abstract Library

#1479 Comparison of Radiological and Histological Tumor Size in Pancreatic Neuroendocrine Neoplasm

Introduction: Radiological tumor size of pancreatic neuroendocrine neoplasms (PNEN) is crucial for management especially for asymptomatic, small lesions.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Polenta V

Authors: Polenta V, Partelli S, Wiese D, Fendrich V, Muffatti F,

Keywords: Pancreatic neuroendocrine neoplasm, size, radiology, pathology, surgery,

#1313 C-Reactive Protein As a New Prognostic Factor for Overall Survival in Patients with Pancreatic Neuroendocrine Neoplasia

Introduction: For many cancer entities, inflammation has been shown to play an important role in pathogenesis and progression.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Fendrich V

Authors: Fendrich V, Wiese D, Kampe K, Heverhagen A, Waldmann J,

Keywords: CRP, prognosis, pNEN, survival,

#746 Aspirin Delays the Development/Progression of Neuroendocrine Pancreatic Neoplasms and Prolongs Survival in a Transgenic Mouse Model of Islet Cell Tumors

Introduction: So far, there are no chemopreventive strategies for neuroendocrine pancreatic neoplasms.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Fendrich V

Authors: Fendrich V, Manoharan J, Lopez C, Waldmann J, Bartsch D,

Keywords: neuroendocrine pancreatic tumors, aspirin, chemoprevention,

#110 Slug represents an important regulator of E-cadherin expression in neuroendocrine tumor cells of the pancreas

Introduction: Neuroendocrine tumors of the pancreas form an inhomogenous group of epithelial neoplasms. They differ from other types of pancreatic cancers by showing an extended survival of patients, which is due to a mostly slow proliferation rate of the tumor. However, some of these neuroendocrine tumors are characterized by an early onset of metastases, which cannot be predicted by any available method. The epithelial to mesenchymal transition (EMT) represents a central part of cell migration and metastasis. During EMT, cells loosen their cellular contacts, leave the tissue, and become migrating single cells. One of the integral compounds of cell adhesion represents the E-cadherin adhesion module, which contains mostly E-cadherin and several catenins. A loss of this adhesion module is associated with tumor progression, migration and metastasis in many types of cancer.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: König A

Authors: König A, Reutlinger K, Ellenrieder V, Gress T, Fendrich V,

Keywords: neuroendocrine tumor of the pancreas, E-cadherin, Slug, cell adhesion,