Abstract Library

#988 Vimentin and E-cadherin Expression in Primary Neuroendocrine Tumors by Grade

Introduction: The prognostic evaluation of radically removed neuroendocrine tumors (NETs) represents an important issue. The cardinal tumor features can be studied as biomarkers.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Vanags A, Strumfa I, Simtniece Z, Vasko E, Gardovskis J,

Keywords: NETs, vimentin, E-cadherin,

#882 Gene Expression Characterization of Gastroenteropancreatic Neuroendocrine Tumors [GEPNETS: Gastrointestinal and Pancreatic NETs (GINETs and pNETs)] and Their Correlation with Clinical Factors and Tumor Behavior

Introduction: GEP-NETs are a heterogenous group of tumors with different molecular backgrounds and clinical outcome.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Martínez-Fuentes A

Authors: Díaz Pérez J, García-Carbonero R, Villabona C, Capdevila J, Jiménez-Fonseca P,

Keywords: sst4, RET, angiogenesis, GEP-NET,

#801 Normal Gastrointestinal Neuroendocrine Cells Lack E-cadherin

Introduction: E-cadherin plays a crucial role in the adhesion between epithelial cells and thus epithelial integrity. Moreover, germ line mutations in the E-cadherin gene (CDH1) causing loss of E-cadherin function (adhesion) leads to hereditary gastric cancer of the diffuse type, according to Laurén. Even sporadic gastric carcinomas of the diffuse type often lose E-cadherin expression due to mutations. Lack of E-cadherin has been recorded at an early phase in such carcinomas.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Hauso �

Authors: Hauso �, Nordbø H, Ringnes E, Sørdal �, Nordrum I,

Keywords: E-cadherin, neuroendocrine cell, gastric cancer, adhesion molecules, neuroendocrine tumors, carcinoid,

#558 MANECs Among Colorectal Signet Ring Cell Carcinomas

Introduction: The mixed adenoneuroendocrine carcinomas (MANEC, WHO 2010) are neoplasms with heterogeneous morphology, whose mixed nature may be difficult to recognize.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Hermann G, Yarom N, Konukiewitz B, Sandbank J, Klöppel G,

Keywords: manec, signet ring cell carcinoma, colon, rectum,

#508 Differential Expression of Markers in a Midgut Carcinoid Tissue Microarray

Introduction: Molecular mechanisms driving well-differentiated midgut carcinoid (MGC) tumors are not well-established. To pursue higher resolution tumor diagnostics, we studied a panel of markers for their expression in MGC, including: serotonin, FGF2, b-catenin, and E-cadherin, in primary, lymph node, and liver metastases.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Liu E, Mikhitarian K, Revetta F, Shi C,

Keywords: midgut carcinoid, immunohistochemistry, markers,