Abstract Library

#4618 The exceptionally rare phenomenon of well-differentiated colon neuroendocrine tumours

Introduction: Colonic neuroendocrine tumours (NETs), excluding rectal NETs, are often described as relatively common and aggressive, with inferior median survival compared to other gastrointestinal (GI) primary sites. However, epidemiological databases may conflate well-differentiated NETs with poorly differentiated NECs, leading to unclear data on prevalence, clinical behaviour, and prognosis of well-differentiated colonic NETs.

Conference:

Presenting Author: Al-Toubah T

Authors: Al-Toubah T, Strosberg J,

Keywords: colon, neuroendocrine tumour, caecum, sigmoid, neuroendocrine neoplasm,

#4481 Predicting peptide receptor radionuclide therapy (PRRT) response through the landscape of the immune microenvironment in neuroendocrine tumours

Introduction: Neuroendocrine tumours (NETs) often have poor prognosis upon metastasis. Peptide receptor radionuclide therapy (PRRT) is a novel treatment leveraging targeted cytotoxicity of radionuclides to efficiently address primary and metastatic tumours of NETs.

Conference:

Presenting Author: Yu J

Authors: Zeng Z, Lu M, Xie Q, Li J, Yang Z,

Keywords: peptide receptor radionuclide therapy, neuroendocrine tumour, tumour immune microenvironment, tumour response, therapeutic effect prediction,

#4058 Carcinoid syndrome caused by pulmonary neuroendocrine tumor liver metastases: A case report

Introduction: Neuroendocrine tumors (NETs) comprise a heterogeneous groups of maliganancies that arise from neuroencrine cells throughout the body and most commonly originate from the small intestine, lung,and rectum. Pulmonary NETs originate from pulmonary neuroendocrine cells that occur as individual cells or small pulmonary neuroendocrine cell. Although carcinoid tumors are considered low or intermediate-grade tumors, they metastasize to regional lymph nodes and distant organs, and the most common sites metastases are the liver and bone.

Conference:

Presenting Author: Tang Y

Authors: Tu R, Tang Y, Wang Y, Zhu Y, Kui X,

Keywords: pulmonary neuroendocrine tumor, liver metastases, Transcatheter Arterial Embolization, chemotherapy,

#4001 Sex differences in survival of neuroendocrine neoplasms (NENs): Comparative study of patients from National Cancer Registration and Analysis Service (NCRAS, UK) and Surveillance, Epidemiology, and End Results (SEER, US) databases

Introduction: It has been reported that sex is an important predictor of survival of NEN patients using data from the UK NCRAS database. The same statistical methods have not been applied to US SEER data.

Conference:

Presenting Author:

Authors: Mortagy M, El Asmar M, Chandrakumaran K, Ramage J,

Keywords: SEER, NCRAS, Neuroendocrine tumor, RMST, Cox regression, Survival analysis, Sex differences, RMTL, Kaplan Meier,

#4000 Prediction of survival for patients with neuroendocrine neoplasms (NENs) using multivariable cox regression and survival nomograms: Data from National Cancer Registration and Analysis Service (NCRAS, UK) Database

Introduction: Multiple nomograms for predicting survival of NENs from surveillance, epidemiology, and end results (SEER) database have been published. To the best of our knowledge, no survival nomogram has been published from NCRAS database

Conference:

Presenting Author:

Authors: Mortagy M, El Asmar M, Chandrakumaran K, Ramage J,

Keywords: SEER, NCRAS, Nomogram, Survival analysis, Cox regression, Interactive web application, neuroendocrine neoplasm,