Abstract Library

#4618 The exceptionally rare phenomenon of well-differentiated colon neuroendocrine tumours

Introduction: Colonic neuroendocrine tumours (NETs), excluding rectal NETs, are often described as relatively common and aggressive, with inferior median survival compared to other gastrointestinal (GI) primary sites. However, epidemiological databases may conflate well-differentiated NETs with poorly differentiated NECs, leading to unclear data on prevalence, clinical behaviour, and prognosis of well-differentiated colonic NETs.

Conference:

Presenting Author: Al-Toubah T

Authors: Al-Toubah T, Strosberg J,

Keywords: colon, neuroendocrine tumour, caecum, sigmoid, neuroendocrine neoplasm,

#4567 Malignant pheochromocytoma with late distant metastases and secondary hypercalcaemia

Introduction: Pheochromocytoma is a rare neuroendocrine tumour of the adrenal medulla. Malignant variants occur with a very low frequency and can be diagnosed only after the spread of distant metastasis.

Conference:

Presenting Author:

Authors: Kirova I, Vandeva S, Markova M, Elenkova A, Robeva R,

Keywords: neuroendocrine, malignant pheochromocytoma, metastasis, hypercalcaemia,

#2767 Rectal NETs and Rectosigmoid Junction NETs May Need to Be Treated Differently

Introduction: Neuroendocrine tumours (NETs) are heterogeneous, and the incidence of colorectal NETs is rapidly increasing.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Cai W

Authors: Cai W, Ge W, Mao J, Hu h,

Keywords: Rectal neuroendocrine tumor, rectosigmoid junction, SEER database, Survival,

#1882 Clinical Nomogram Development and Predictive Utility for Appendiceal and Colorectal NETs

Introduction: Nomograms are predictive tools that help prognosticate. A survival nomogram has been validated for small bowel NETs has been adapted for other sites. About 50% of NETs occur in the appendix-colon-rectum. Locations have widely differing outcomes (survival 50-100%).

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Kidd M

Authors: Kolasińska-Ćwikła A, Ćwikła J, Kidd M, Bodei L, Lewczuk A,

Keywords: Nomogram,

#1572 Study of the Biological Significance of the IGF-IEc (MGF) in Well and Poorly Differentiated Neuroendocrine Neoplasms

Introduction: Insulin-like growth factor-I (IGF-I) has a key role in cell proliferation, differentiation, migration, and survival. Different IGF-I mRNA transcripts, such as IGF-IEc (mechano growth factor, MGF), are produced by alternative splicing. MGF has been implicated in muscle regeneration process as well as in the pathophysiology of various types of cancer.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Alexandraki K

Authors: Alexandraki K, Philippou A, Boutzios G, Theohari I, Moschouris P,

Keywords: Neuroendocrine neoplasms, MGF, IGF-IEc, ki-67,