Abstract Library

#4634 Management of hypercalcaemia of malignancy in neuroendocrine tumour patients – A case series

Introduction: Hypercalcaemia of malignancy (HM) rarely coexists with neuroendocrine tumours (NET). There are no precise guidelines for management of hypercalcaemia in NET.

Conference:

Presenting Author:

Authors: Klepinowska M, Sagan K, Brzeska A, Andrysiak-Mamos E, Kiedrowicz B,

Keywords: hypercalcaemia of malignancy, neuroendocrine tumour, pancreatic neuroendocrine tumour, hypercalcaemia,

#4567 Malignant pheochromocytoma with late distant metastases and secondary hypercalcaemia

Introduction: Pheochromocytoma is a rare neuroendocrine tumour of the adrenal medulla. Malignant variants occur with a very low frequency and can be diagnosed only after the spread of distant metastasis.

Conference:

Presenting Author:

Authors: Kirova I, Vandeva S, Markova M, Elenkova A, Robeva R,

Keywords: neuroendocrine, malignant pheochromocytoma, metastasis, hypercalcaemia,

#4416 Medicine treatment of functional pancreatic neuroendocrine tumour with hypercalcaemia

Introduction: Functional pancreatic neuroendocrine tumours (F-PNETs) are capable of secreting parathyroid hormone-related protein (PTHrP), causing humoral hypercalcaemia of malignancy (HHM).

Conference:

Presenting Author: Yingmei T

Authors: Yanping Z, Jieting D, Yingmei T, Rongfang T, Yan W,

Keywords: functional pancreatic neuroendocrine tumour, parathyroid hormone related peptide, hypercalcaemia,

#855 Extrapulmonary Small Cell Neuroendocrine Carcinoma of the Colon in an 18-Year-Old Girl

Introduction: Extrapulmonary small cell carcinoma (EPSCC) is a very rare aggressive malignant tumor typical for older age. Prognosis of EPSCC remains very poor, with three years OS 38% and five years OS less than 13%. The median survival for GI localised EPSCC is only five months. Initial extent of disease is the most sensitive prognostic factor.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Bajciova V

Authors: Bajciova V, Kren L, Oltova A,

Keywords: colon EPSCC, young age,

#492 Should Primary Hyperparathyroidism at Age Below 40 Years Always Lead to Search for MEN-1, Despite Presence of Other Plausible Explanations?

Introduction: A 30-year-old female patient with inherited osteogenesis imperfecta (OI) Type 1 was referred due to hypercalcaemia and suspicion of primary hyperparathyroidism (pHPT). She had serum ca2+ 1.56 mmol/L, serum parathyroid hormone 115 ng/ml (< 70), and pHPT was diagnosed, but no scan uptake. By exploratory neck surgery, all parathyroid glands were hyperplastic and 3 ½ parathyroid + thymus were removed. The HPT was hypothesised to be due to abnormal calcium metabolism from OI (J Endocrinol Invest 1999), although not described previously.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Feldt-Rasmussen U, Rasmussen �, Friis-Hansen L,

Keywords: MEN-1, screening, pHPT,