Abstract Library

#4537 The usefulness of circulating fibrosis markers in detection of carcinoid heart disease

Introduction: Carcinoid heart disease (CHD) is a potential serious fibrotic complication in patients with neuroendocrine neoplasms (NENs), affecting the heart valves. Early detection is crucial to avoid severe manifestations. NT-proBNP is suggested as an initial screening tool in detection of CHD; however, the value of NT-proBNP as a screening tool is questionable.

Conference:

Presenting Author: Lau T

Authors: Lau T, Angeli E, Oksjoki R, Rasmussen V, Genovese F,

Keywords: carcinoid heart disease, biomarker, fibrosis marker,

#4110 The role of fibrosis markers in predicting decline in renal function in patients undergoing PRRT

Introduction: Renal impairment due to renal fibrosis is a potential side effect in NET-patients undergoing Peptide Receptor Radionuclide Therapy (PRRT). Fibrosis markers are small collagen formation - and degradation fragments that are measurable in circulation at very early stages of fibrosis formation.

Conference:

Presenting Author: Lau T

Authors: Lau T, Bossen L, Rasmussen D, Karsdal M, Genovese F,

Keywords: PRRT, Biomarker, Fibrosis Marker,

#3634 Imaging surveillance in multiple endocrine neoplasia type 1 – 10 years of experience with somatostatin receptor positron emission tomography

Introduction: Guidelines for multiple endocrine neoplasia type 1 (MEN1) recommend intensive imaging surveillance without specifying a superior regimen, including the role of somatostatin receptor imaging (SRI) with positron emission tomography (PET).

Conference:

Presenting Author: Andreassen M

Authors: Said M, Krogh J, Feldt-Rasmussen U, Rasmussen �, Kristensen T,

Keywords: Imaging, Multiple endocrine neoplasia type 1, Neuroendocrine neoplasm, Positron emission tomography, Somatostatin receptor,

#1762 Prevalence of Carcinoid Heart Disease in Patients with Disseminated Small Intestinal NET

Introduction: In patients with small intestinal neuroendocrine tumours (SI-NETs), serotonin may induce fibrosis and lead to carcinoid heart disease (CHD) with right sided valvular dysfunction.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Groenbaek H

Authors: Dam G, Rasmussen V, Oksjoki R, Villadsen G, Grønbæk H,

Keywords: carcinoid heart disease, SI-NET,

#1167 Cowden Syndrome and Concomitant Pulmonary Neuroendocrine Tumor: A Presentation of Two Cases

Introduction: Cowden Syndrome is a multiorgan disorder with germline mutations in the tumor suppressor gene PTEN leading to dysfunctional cell growth and risk of neoplasms in e.g. breast and thyroid, but no association with NET has been described.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Ringholm L

Authors: Ringholm L, Langer S, I Dali C, Petersen R, Rasmussen A,

Keywords: Cowden Syndrome, pulmonary NET,