The exceptionally rare phenomenon of well-differentiated colon neuroendocrine tumours

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Introduction: Colonic neuroendocrine tumours (NETs), excluding rectal NETs, are often described as relatively common and aggressive, with inferior median survival compared to other gastrointestinal (GI) primary sites. However, epidemiological databases may conflate well-differentiated NETs with poorly differentiated NECs, leading to unclear data on prevalence, clinical behaviour, and prognosis of well-differentiated colonic NETs.

Aim(s): To identify and characterise patients with well-differentiated NETs originating in the colon (excluding rectum), analysing their prevalence, grade, stage, and prognosis.

Materials and methods: A large institutional database was analysed to identify patients with well-differentiated NETs originating in the colon. Caecal NETs were included, while ileocecal NETs (overlapping the ileocecal valve) were excluded. Data on prevalence, grade, stage, and prognosis was collected.

Conference:

Presenting Author: Al-Toubah T

Authors: Al-Toubah T, Strosberg J,

Keywords: colon, neuroendocrine tumour, caecum, sigmoid, neuroendocrine neoplasm,