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#30 Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia

Introduction: Normal adult lungs contain scattered pulmonary neuroendocrine cells (PNEC). Reactive PNEC hyperplasia is commonly observed in persons who live at high altitude, in cigarette smokers, and in numerous lung diseases. Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) is a rare entity in which PNEC hyperplasia appears without predisposing conditions. According to the 1999 WHO lung tumor classification, DIPNECH is thought to be primarily a neuroendocrine proliferative process, which can be associated with carcinoid tumors and with a clinical picture of constrictive obliterative bronchiolitis. To date, available data regarding the treatment and the prognosis of this rare condition is limited.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Grozinsky-Glasberg S

Authors: Gorshtein A, Barak D, Shimon I, Gross D, Grozinsky-Glasberg S,

Keywords: DIPNECH, neuroendocrine, hyperplasia, somatostatin analogues,