Abstract Library

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#1066 The Impact of Pharmacological-Mediated Depletion of Macrophages in Pancreatic Neuroendocrine Neoplasms

Introduction: Pancreatic neuroendocrine tumors (PNETs) are a heterogeneous group of neuroendocrine neoplasms with distinct biological behaviour and response to treatment. Previous reports indicate that the infiltration of tumor-associated macrophages (TAMs) in PNETs strongly correlates with proliferation and metastases.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Krug S

Authors: Krug S, Abbassi R, Rinke A, Griesmann H, Gress T,

Keywords: clodro, TAM, RIP1-Tag2,

#488 CUX1 Mediates Progression of Neuroendocrine Tumors

Introduction: CUX1 is a key mediator of tumor progression in pancreatic ductal adenocarcinoma (PDAC) and is upregulated during tumorigenesis in PDAC. It contributes to tumor invasion and is resistant to apoptosis and angiogenesis.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Krug S, Kühnemuth B, Griesmann H, Kortenhaus J, Lankat-Buttgereit B,

Keywords: CUX1, angiogenesis ,