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#205 Integrated Genome-Wide DNA Methylation and mRNA Expression Analysis of Pancreatic NETs Identifies Differential Activation of the Hypoxia Inducible Factor (HIF) Pathway Between Low and Intermediate Grade Tumors

Introduction: This is the first study to integrate DNA methylation and mRNA expression analysis in NETs. It is a powerful approach with which to identify disrupted biological pathways in NET pathogenesis.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Thirlwell C, Schulz L, Eymard M, Luong T, Meyer T,

Keywords: pancreatic neuroendocrine tumor, hypoxia inducible factor, DNA methylation, HIF1-a, IGF1,