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#2685 Apatinib Inhibits Tumor Growth and Angiogenesis in PNET Models

Introduction: Angiogenesis has a pivotal role in the growth and metastasis of pancreatic neuroendocrine tumors (PNETs). Apatinib inhibits angiogenesis as a highly selective KDR inhibitor and has been used to treat advanced gastric cancer and malignancies in clinical settings. However, the efficacy of apatinib in PNETs remains unclear.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Wang z

Authors: Wu S, Zhou J, Guo J, Hua Z, Li J,

Keywords: Pancreatic neuroendocrine tumors, angiogenesis, KDR, apatinib, liver metastasis,

#823 Association Between Tumor Expression of VEGFA, VEGFR1 (FLT1), VEGFR2 (KDR), and Clinical Outcomes in Neuroendocrine Tumors

Introduction: Clinical studies have suggested efficacy of VEGF pathway inhibitors in the treatment of advanced neuroendocrine tumors (NETs).

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Qian Z

Authors: Qian Z, Ter-Minassian M, Chan J, Imamura Y, Hooshmand S,

Keywords: VEGF, bevacizumab, NET survival,