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#1641 Somatostatin Receptor Expression in Adrenocortical Carcinoma

Introduction: Adrenocortical carcinoma (ACC) is an uncommon neoplasm with an estimated annual incidence of 0.5-2 cases per million population. Surgery of the adrenal tumor is the major treatment. When complete tumor removal is not possible, or in case of recurrence, medical treatment with O,p’DDD(mitotane) is recommended. The treatment of ACC is currently based on the mitotane partial responses have been described in 19-34% of cases, and there are single reports of complete responses.The discovery of somatostatin (SST) and the identification of stable SST analogs with a longer half-life have raised new hopes for the treatment of endocrine tumors.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Voronkova I, Gurevich L, Kazanceva I, Krivosheev A, Britvin T,

Keywords: Adrenocortical carcinoma, Somatostatin receptor, Immunohistochemistry,