Abstract Library

#1689 The Prognostic Value of the Expression of Cytokeratin 7 and 19 in Lungs and Pancreas Neuroendocrine Tumors

Introduction: The expression of cytokeratins (CK) 7,19 rarely occurs in the low grade neuroendocrine tumors (NET) of lung and pancreas. It is known that part of the low grade typical (TC) and atypical (ATС) carcinoids of lung and pancreas (pNET-G1,G2) can progress quickly and to metastasize. It is important to distinguish NET with a less differentiated cells immunophentype.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Gurevich L, Korsakova N, Voronkova I, Kazanceva I, Ashevskaya V,

Keywords: neuroendocrine tumors, cytokeratin 7, 19 expression, lung, pancreas, prognostic factors,

#1641 Somatostatin Receptor Expression in Adrenocortical Carcinoma

Introduction: Adrenocortical carcinoma (ACC) is an uncommon neoplasm with an estimated annual incidence of 0.5-2 cases per million population. Surgery of the adrenal tumor is the major treatment. When complete tumor removal is not possible, or in case of recurrence, medical treatment with O,p’DDD(mitotane) is recommended. The treatment of ACC is currently based on the mitotane partial responses have been described in 19-34% of cases, and there are single reports of complete responses.The discovery of somatostatin (SST) and the identification of stable SST analogs with a longer half-life have raised new hopes for the treatment of endocrine tumors.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Voronkova I, Gurevich L, Kazanceva I, Krivosheev A, Britvin T,

Keywords: Adrenocortical carcinoma, Somatostatin receptor, Immunohistochemistry,