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Introduction: Immuno check-point inhibitors development in grade 1-2 NENs is limited by low mutation tumor load and PD-1/PDL-1 expression. The combination of an PDL-1 and CTLA-4 inhibitors could increase the probability of success in this setting. In high grade NENs the rational for immunotherapy is stronger based on experiences in small cell lung cancer.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Hernando-Cubero J
Authors: Hernando-Cubero J, Manzano J, Benavent M, Lopez C, Teulé R,
Keywords: Durvalumab, Tremelimumab, Neuroendocrine, Immunotherapy,
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