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Introduction: The control of hypoglycemic hyperinsulinemic syndrome from malignant insulinoma is challenging because it is often refractory to diazoxide and somatostatin analogues (SA). Everolimus can have side effects that can limit its use. Pasireotide, a multi-receptor-targeted SA with a high binding affinity to SSTR1 and SSTR5, exhibits a strong inhibitory effect of insulin secretion.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Davi' M
Authors: Zambon G, Cosaro E, Cingarlini S, Trombetta M, Landoni L,
Keywords: pasireotide, malignant insulinoma, hypoglycemia,
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