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Introduction: A proportion of diffuse gastric carcinoma, according to the Lauren classification system, has signet ring cell morphology. Signet ring cells are characterized by a peripherally placed nucleus and a central amorphous substance, which is reported to be mucin based on Periodic Acid Schiff positivity (PAS). PAS is not a specific staining method for mucin. Neuroendocrine expression has previously been reported in tumor cells in diffuse type gastric cancer.
Conference: 10th Annual ENETSConcerence (2013)
Presenting Author: Sørdal �
Authors: Sørdal �, Qvigstad G, Nordrum I, Waldum H,
Keywords: gastric signet ring cell carcinoma, mucin, neuroendocrine markers, PAS,
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