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#4372 CVM-005: A multicentre, single-arm, phase IIa study of CVM-1118, a novel oral anti-vasculogenic mimicry (VM) agent, in patients with treatment-refractory advanced neuroendocrine tumours (NET)

Introduction: NETs are highly vascularised tumours and a viable target for anti-VM therapies. CVM-1118 is an anti-tumour agent with multiple MOAs, including disruption of VM networks and induction of apoptosis via targeting mitochondrial TRAP1 protein.

Conference:

Presenting Author: Yen C

Authors: Yen C, Chen M, Chen Y, Bai L, Chen J,

Keywords: CVM-1118, GEP-NET, anti-vasculogenic mimicry,