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#4187 Psychiatric and cognitive function in patients with serotonin producing neuroendocrine tumors

Introduction: Cognitive and psychiatric problems are common in cancer patients, but literature in patients with neuroendocrine tumors (NET) is scarce. Peripheral serotonin overproduction by the tumor, clinically manifesting as carcinoid syndrome, is hypothesized to be related to cognitive and psychiatric problems, through depletion of serotonin’s precursor tryptophan.

Conference:

Presenting Author: Tesselaar M

Authors: Luijendijk M, Tesselaar M, van Rossum H, Korse C, Verbeek W,

Keywords: Neuroendocrine neoplasm, carcinoid syndrome, cognitive functioning, depression, anxiety, serotonin, tryptophan, 5-HIAA,