Abstract Library

#3959 Sortilin: A novel marker and potential therapeutic target for functional neuroendocrine tumors

Introduction: A subset of neuroendocrine tumors (NETs) causes a hormone-related disease (functional syndrome); e.g. carcinoid syndrome due to over-secretion of mainly serotonin. Notably, on a molecular level, what distinguishes this subset of functional NETs from nonfunctional tumors is unknown. Furthermore, accurate models of functional NETs are missing. Sortilin, a widely expressed transmembrane receptor, is expressed in many cancer cells, including NETs, and is involved in secretion processes.

Conference:

Presenting Author: Bolduan F

Authors: Bolduan F, Wetzel A, Giesecke Y, Eichhorn I, Alenina N,

Keywords: Neuroendocrine tumor, Functional syndrome, Carcinoid syndrome, Serotonin, Sortilin, Organoids, Enteroendocrine cells,

#2960 Epidemiological Characteristics of Neuroendocrine Tumors: A Retrospective Analysis of a Single Centre

Introduction: Neuroendocrine tumors (NETs) are a small heterogeneous group of cancers, developing from the neuroendocrine system. NETs may include functional or non-functional tumors; moreover, they may be familial and have further associated tumors.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Giuffrida D

Authors: Puliafito I, Blanco G, Sciacca D, Colarossi C, Leotta E,

Keywords: neuroendocrine, tumors, our, retrospective, analysis,

#2867 Experience of Treatment with Everolimus in Patients with Well-Differentiated Neuroendocrine Tumors (NET) of Various Localizations at the NN Blokhin NMRCO, Moscow, Russia

Introduction: Everolimus (EVE) (mTOR inhibitor) is an effective drug in the treatment of well-differentiated NETs of different localizations, however, prognostic factors for the correct choice of therapy are not well understood.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Markovich A, Kuznetsova A, Gorbunova V, Orel N, Emelianova G,

Keywords: neuroendocrine tumors, everolimus, uni- and multivariate analysis,

#950 Outcome of Malignant Insulinomas (MI) in the Community Setting

Introduction: MI is a rare and difficult to handle functional pancreatic neuroendocrine tumor with a variety of therapeutic alternatives.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Lopez C, Capdevila J, Jiménez-Fonseca P, Custodio A, Crespo G,

Keywords: insulinoma, pNET, functional tumors,

#410 Pancreatic Neuroendocrine Tumors: Retrospective Analysis Of 44 Cases

Introduction: Neuroendocrine tumors (NETs) are heterogeneous neoplasms. Pancreatic NETs (pNETs) have a broad spectrum of features. Bioamines and peptides production distinguish functional from nonfunctional tumors.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Marques P, Barata P, Santos R, Martins A, Leite V,

Keywords: neuroendocrine tumors, pancreatic tumors, insulinoma, gastrinoma,