Abstract Library

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ENETS Abstract Search

#3057 Epidemiological Features of Patients with NeuroEndocrine Neoplasms (NENs): Preliminary Results of an Observational Study by the Hellenic Society of Medical Oncology (HeSMO)

Introduction: NENs are rare tumors and can grow in almost all tissues. Regardless histological, molecular and imaging characteristics that are indicative of the primary origin, a significant percentage remain of unknown primary.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Koumarianou A

Authors: Koumarianou A, Tsoukalas N, Syrigos K, Demiri S, Ziras N,

Keywords: NeuroEndocrine Neoplasms (NENs), epidemiological features, registry, diagnosis, Hellenic Society of Medical Oncology (HeSMO),

#3056 Multi-Omic Characterization and Evolution of Neuroendocrine Neoplasm Organoids

Introduction: Molecular characterizations of neuroendocrine neoplasm (NENs) have unveiled candidate alterations associated with aggressiveness and suggested that the molecular link between neuroendocrine tumors (NETs) and neuroendocrine carcinomas (NECs) might be subtler than initially thought. For example, we have recently unveiled a new entity of pulmonary carcinoids (supra-carcinoids) with carcinoid-like morphology yet the molecular and clinical features of large cell neuroendocrine carcinoma (LCNEC). Testing hypotheses to explain aggressiveness and the possibility of progression or transition from NET to NEC through the accumulation of genetic anomalies requires in vitro and in vivo experimental models.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Foll M

Authors: Alcala N, Dayton T, Mangiante L, Delhomme T, Tabone-Egling S,

Keywords: organoids, omics, evolution, lung, pancreas, bioinformatics,

#3028 Pancreatic Neuroendocrine Neoplasms: Dissecting the Molecular Heterogeneity

Introduction: Pancreatic neuroendocrine neoplasms (PNENs) are a group of rare but biologically and clinically heterogeneous neoplasms with variable patient outcomes. Little is known about the molecular differences between PNENs and the biologic significance of such divergence.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Yang K, Kalloger S, Aird J, Lee M, Colborne S,

Keywords: Pancreatic neuroendocrine neoplasms, Exome, Transcriptome, Proteome,

#3011 Added Prognostic Value of Molecular Imaging Biomarkers over Proliferation Index in Typical Lung Carcinoid: An FDG PET and SSTR Imaging Study

Introduction: Typical lung carcinoids(TCs)are rare tumors with good,although heterogeneous,prognosis.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Briganti V

Authors: Briganti V, Berti V, Abenavoli E, Linguanti F, Ciaccio A,

Keywords: typical lung carcinoid, FDG PET, SSTR imaging, MTV, TLG,

#2992 The PanNENomics Project: A Call for an International Collaborative Effort Built on the Success of the LungNENomics Project

Introduction: Neuroendocrine tumors are rare understudied diseases at the molecular level, especially those occurring in sites outside the lung and the gastrointestinal track. This lack of knowledge has strong implications for the clinical management of these diseases (Rindi et al. Mad Pathol 2018).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Fernandez-Cuesta L

Authors: Fernandez-Cuesta L, Foll M, Walter T, Girard N, Lantuejoul S,

Keywords: Rare Cancers genomics, lungNENomics, panNENomics, supra-carcinoids, tumor maps,