Abstract Library

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#2035 Prevalence of Carcinoid Syndrome (CS) in the European Union (EU)

Introduction: Epidemiologic data on CS, which typically occurs in patients with advanced midgut or lung neuroendocrine tumors (NET), are scarce and appear to be heterogeneous across countries.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Nayroles G

Authors: Nayroles G, Bergamasco A, Mouchet J, Moride Y,

Keywords: neuroendocrine tumors, carcinoid syndrome, prevalence rate, orphan disease, Europe,

#427 Gastric Carcinoids: Prevalence in Europe and USA, and Rationale for Treatment with YF476, a Gastrin Receptor Antagonist

Introduction: Gastric carcinoids (GC) are tumors arising from enterochromaffin-like (ECL) cells in the gastric mucosa. Most are caused by hypergastrinaemia, which stimulates ECL-cell growth. YF476 is a potent, selective and orally active gastrin receptor antagonist in humans in vitro and in vivo. YF476 prevented and caused shrinkage of GC in animal models of the condition.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Boyce M,

Keywords: gastric carcinoids, ECL cells, YF476, OMP,