ACTH-secreting pancreatic neuroendocrine neoplasms – A case-series

#3728

Introduction: Ectopic Cushing’s syndrome occurs rarely in patients with pancreatic neuroendocrine neoplasms. Early recognition of symptoms is critical given the high morbidity and mortality associated with Cushing’s syndrome.

Aim(s): Describe the presentation of Ectopic Cushing's syndrome in pancreatic NENs and discuss best therapeutic strategies.

Materials and methods: A database of pancreatic NENs seen at the Moffitt Cancer Center between 1/2008 and 4/2022 was reviewed and cases of ectopic Cushing’s syndrome were identified. Information was extracted on tumor characteristics, clinical signs and symptoms, therapies, and outcomes.

Conference:

Presenting Author: Al-Toubah T

Authors: Al-Toubah T, Pelle E, Hallanger-Johnson J, Haider M, Strosberg J,

Keywords: pancreatic neuroendocrine neoplasm, Cushing’s syndrome, ACTH, ectopic Cushing’s, neuroendocrine tumor,