Abstract Library

#2885 Ectopic Neuroendocrine Carcinoma: An Occult Source of ACTH

Introduction: About 250 cases of ectopic ACTH-producing neuroendocrine carcinoma (ACTH-NEC) have been reported; however metastatic ACTH-NEC of unknown primary is very rare. Usually are characterized by having a large cell, small cell, poorly differentiated or anaplastic cell, and Ki-67 index between 40-90%.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Alvaréz Figueroa J, Aguirre Matallana D, Cañón Solano D,

Keywords: Ectopic ACTH production, Cushing’s syndrome, Neuroendocrine carcinoma, Paraneoplastic Cushing syndrome, Ectopic Cushing´s syndrome,

#2233 Potential Effects of Ketoconazole on ACTH-Producing and Non-ACTH-Producing Neuroendocrine Tumors

Introduction: Prolonged biochemical remission after treatment with steroidogenesis inhibitors has been described in patients with Cushing’s syndrome due to ectopic adrenocorticotropin hormone (ACTH) production. Some studies have suggested antiproliferative and apoptotic effect of ketoconazole in human cancer cells.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Herrera-Martínez A

Authors: Herrera-Martínez A, Feelders R, Castaño J, Van Dungen R, Dogan-Oruc F,

Keywords: ACTH- and non-ACTH producing NETs, ketoconazole, somatostatin analogs, apoptosis, cytotoxicity,

#2193 Advanced Gastric Neuroendocrine Carcinoma: A Diagnostic and Management Conundrum

Introduction: Gastric neuroendocrine carcinomas are rare tumors with a high malignant trait and poor prognosis. Endogenous hypercortisolism associated with neuroendocrine carcinomas can have a negative impact on patients' survival.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Lambrescu I, Martin S, Nitipir C, Terzea D, Cima L,

Keywords: gastric neuroendocrine carcinoma, hypercortisolism, Cushing disease, ectopic ACTH,

#2029 Prognostic Factors of Pulmonary Carcinoid Tumors

Introduction: Pulmonary carcinoids (PC) are rare malignant neoplasms that account for approximately 1% of all lung cancers. PCs are classified by histological criteria as either typical (TC) or atypical (AC). Histological subtype is the most studied prognostic factor.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Vesterinen T

Authors: Vesterinen T, Mononen S, Salmenkivi K, Mustonen H, Ilonen I,

Keywords: pulmonary carcinoids, prognosis,

#1838 A Rare Case of Ectopic Cushing's Syndrome

Introduction: Cushing's syndrome has an incidence of 0.7 - 2.4 per million people per year. In 15% of cases, it’s associated with non-pituitary tumors secreting ACTH. Pheochromocytoma accounts for 5% of ectopic ACTH secretion.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Steina L

Authors: Steina L, Steina S, Pirags V, Ozolins A, Gardovskis J,

Keywords: malignant pheochromocytoma,