Adverse events after endoscopic ultrasound-guided fine-needle aspiration and fine-needle biopsy in pancreatic neuroendocrine tumors: A systematic review

#4118

Introduction: Pathological analysis of pancreatic neuroendocrine tumors (pNET) is essential for predicting tumor behaviour and patient management. Although endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is the established practice for retrieving tissue, fine-needle biopsy (EUS-FNB) offers possibilities for additional analyses including tumor grading. This systematic review provides a comprehensive evaluation of EUS-FNA and EUS-FNB-related adverse events in pNET.

Aim(s): The aim of this study was to compare the rate of adverse events after EUS-FNA vs EUS-FNB for pNET.

Materials and methods: EMBASE, OVID/Medline and Clarivate Analytics/Web of Science Core Collection were searched up to February 14th, 2023 to identify studies reporting adverse events after EUS-FNA and/or EUS-FNB in solid pNET. This study adhered to PRISMA and CHARMS guidelines, and critical appraisal was performed.

Conference:

Presenting Author: Chen J

Authors: Chen J, Verschuur A, Abdelmonem A, Dreijerink K, Engelsman A,

Keywords: pancreatic neuroendocrine tumor, EUS-FNA, EUS-FNB, adverse events, systematic review,