ALPPS as a Technique to Minimize Small For Size Syndrome after Major Hepatectomy for Neuroendocrine Tumour Metastases.

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Introduction: Liver resection has emerged as an effective treatment for secondary liver neuroendocrine tumours. “Associated liver partition and portal vein ligation for staged hepatectomy” (ALPPS) allows resection of liver tumours in 2 steps.

Aim(s): We present our experience in ALPPS procedure as a method which can minimize small for size syndrome, and provide an oncological benefit to borderline resectable neuroendocrine tumours within acceptable safety profile.

Materials and methods: 4 patients underwent ALPPS procedure for clearance of the metastatic liver disease. Segments I, IV-VIII were resected for each patient. 2 of the patients had bi-lobar disease. Clearance to the future liver remnant (FLR) was achieved with non-anatomical liver resection in 1 case and with irreversible electroporation to the other as the lesion was adjacent to the left hepatic vein during the 1st stage of the ALPPS procedure. 2 patients underwent ALPPS as a salvage procedure after failed portal vein embolisation and ligation respectively.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Pizanias M

Authors: Pizanias M, Papamichail M, Kontis E, Prassas E, Ramage J,

Keywords: ALPPS, neuroendocrine, hepatectomy,