Can simple measurements on routine surveillance CT in metastatic NET disease predict clinically significant carcinoid heart disease? A retrospective single site study of 73 patients

#3669

Introduction: Patients with confirmed metastatic neuroendocrine tumors (MNET) have surveillance CT scan, therefore there is acquisition of non-gated cardiac imaging.

Aim(s): We present preliminary data investigating the screening of carcinoid heart disease (CHD) in MNET. We investigated simple measurements on CT thorax that may be helpful detecting the presence of CHD.

Materials and methods: This retrospective single centre study was performed on 73 tertiary cardiology service patients with suspicion of CHD. All patients had CT scans before and after referral. We investigated the CT scan nearest to the referral date prior to cardiology intervention. We measured simple non-gated cardiac CT parameters and assessed for differences in groups with confirmed CHD (41 patients) and with no evidence of CHD (32 patients) after extensive cardiology investigation. Parameters include maximum axial short axis of both ventricular internal diameters and ratio (RV/LV), maximum axial long axis of both atrial internal diameters and their ratio (RA/LA). We calculated the dispersion measures and unpaired t-tests. 3 parameters were statistically significant.

Conference:

Presenting Author: Alessi A

Authors: Alessi A, Hughes S, Steeds R, Shah T, El-Sayed M,

Keywords: MNET, CHD, non-CHD,