Comparable survival benefit of surgical approaches for small grade 1 pancreatic neuroendocrine tumors – A propensity score matching study

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Introduction: Pancreatic neuroendocrine tumors (pNETs) are rare neuroendocrine tumors (NETs) for which little is known about their treatment option. The optimal surgical management for small grade 1 pNETs (G1 pNETs) is still a matter of debate.

Aim(s): To explore the optimal surgical approach for the patients with small G1 pNETs and to provide a new theoretical basis for treatment.

Materials and methods: A retrospective analysis of individuals with ≤20mm G1 pNETs registered in the Surveillance, Epidemiology, End Results (SEER) database was performed. The 1:2 propensity score matching (PSM) method was used to balance the imbalanced baseline covariates (P＜0.05) between the groups. A Cox proportional hazards model was used to identify the risk factors associated with cancer-specific survival (CSS) and overall survival (OS).

Conference:

Presenting Author: Chen J

Authors: Chen J, Jiang Y, Chen Q, Deng Y, Zhao H,

Keywords: Pancreatic neuroendocrine tumor, Surgery, Prognosis, SEER,