Abstract Library

#4490 Parietal cell-selective Slc26a9 deletion in mice causes gasdermin D mediates mitochondrial damage and pyroptosis, which is the key event to induce autoimmune gastritis

Introduction: Autoimmune gastritis (AIG) is the basis of gastric malignancy, including neuroendocrine tumour (NET) and gastric cancer (GC). We reported that Slc26a9 is highly expressed in parietal cells (PCs), and its deficiency caused GC.

Conference:

Presenting Author: Liu X

Authors: Ji B, Deng Z, Ma Z, Li T, Tuo B,

Keywords: Slc26a9, autoimmune gastritis, Pyroptosis, gastric mucosal immunity remodelling,

#4435 Clinicopathological characteristics and prognosis of 12191 patients with pancreatic neuroendocrine neoplasms

Introduction: Pancreatic neuroendocrine neoplasms (P-NENs) are a group of tumours originating from pancreatic neuroendocrine cells. Although these tumours are relatively rare, studies on them have gradually increased in recent years.

Conference:

Presenting Author:

Authors: Han D, Du H,

Keywords: Pancreatic neuroendocrine neoplasm, Multivariate analysis, Surgery,

#4400 Analysis of clinicopathologic features and prognosis of 8096 patients with gastric neuroendocrine neoplasms

Introduction: Gastric neuroendocrine neoplasms (G-NENs), as rare tumours, continue to increase in morbidity and mortality. The specificity of the clinical features of G-NENs has led to a lack of awareness of this disease.

Conference:

Presenting Author:

Authors: Han D, Du H,

Keywords: Gastric neuroendocrine neoplasm, Clinicopathologic features, Prognosis,

#4298 Clinicopathologic characteristics and prognosis of 581 cases of hepatic neuroendocrine tumours

Introduction: Hepatic neuroendocrine tumours (PHNETs) are a rare type of liver tumour that originate from neuroendocrine cells in the liver. Compared to other types of liver tumours such as hepatocellular carcinoma, research on PHNETs is relatively scarce.

Conference:

Presenting Author:

Authors: Han D, Du H,

Keywords: Hepatic neuroendocrine tumour, Prognosis, Clinicopathologic features,

#4113 Establishment of a rat model of diarrhea induced by Surufatinib

Introduction: Surufatinib is a novel oral small-molecule TKI for the treatment of advanced neuroendocrine tumors. However, diarrhea is a common adverse event of surufatinib which can affects patients’ quality of life and clinical efficacy. Currently, there are no available animal models to study the cause and treatmen of surufatinib-related diarrhea.

Conference:

Presenting Author: Hu S

Authors: Hu S, Guo Y, Chen Y, Cheng Z, Deng C,

Keywords: Surufatinib, diarrhea, model, rat,