Diagnostic work-up for neuroendocrine tumors of occult primary at diagnosis: A retrospective monocentric study of 60 cases

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Introduction: Neuroendocrine tumors (NET) are sometimes diagnosed with an occult primary. Identifying the primary and ruling-out unknown primary NET (NET-UP) has therapeutic implications.

Aim(s): To analyse the primary site identification work-up (imaging, pathology, biology etc) and to study the outcomes.

Materials and methods: We conducted a retrospective single-centre study including patients with occult primary NET at initial diagnosis between 1998 and 2022 at Gustave Roussy and collected data regarding clinical, biological, histological, molecular, imaging and treatment features.

Conference:

Presenting Author: Roy M

Authors: Roy M, Fodil-Cherif S, Moog S, Lamarta L, Planchard D,

Keywords: neuroendocrine neoplasm, cancer of unknown primary, diagnosis,