Abstract Library

#4463 Evaluating multi-visceral resection for locally advanced and metastatic pancreatic neuroendocrine tumours (PNETs): Feasibility, safety and complications

Introduction: Pancreatic neuroendocrine tumours (PNETs) are rare but clinically significant neoplasms. Surgery can play a significant role in the multimodal treatment of PNETs. Multi-visceral resection involving organs in the left upper quadrant (LUQ) can be used with curative or cytoreductive intent in selected cases.

Conference:

Presenting Author:

Authors: Ee J, Patel R, Hamady Z, Pike T, Karavias D,

Keywords: neuroendocrine, tumour, pancreatic, multivisceral,

#4164 Diagnostic work-up for neuroendocrine tumors of occult primary at diagnosis: A retrospective monocentric study of 60 cases

Introduction: Neuroendocrine tumors (NET) are sometimes diagnosed with an occult primary. Identifying the primary and ruling-out unknown primary NET (NET-UP) has therapeutic implications.

Conference:

Presenting Author: Roy M

Authors: Roy M, Fodil-Cherif S, Moog S, Lamarta L, Planchard D,

Keywords: neuroendocrine neoplasm, cancer of unknown primary, diagnosis,

#4129 Validation of a radiomics model to predict symptoms complications from small intestinal NET mesenteric metastases – Preliminary report

Introduction: The development of mesenteric metastases and associated mesenteric fibrosis in small intestinal neuroendocrine tumors (SI-NET) can cause significant complications and have implications in patients’ survival. CT is suboptimal for accurate assessment of the degree of fibrosis and prediction of complications. A better model is needed, therefore, in order to select patients who may benefit from a prophylactic surgical approach in the mesentery. Recently the promising role of a radiomics model was shown as a predictive tool for development of complications of mesenteric metastases/fibrosis in 68 patients.

Conference:

Presenting Author:

Authors: von Stempel C, Blazevic A, Starmans M, d' Afflitto M, de Herder W,

Keywords: small intestinal neuroendocrine tumor, mesenteric fibrosis, complications, radiomics,

#4092 Liver transplantation for neuroendocrine tumor liver metastases: UK and Ireland’s pioneering pilot programme

Introduction: The incidence of neuroendocrine tumours (NETs) continues to rise. Liver metastases (LM) are commonly present at diagnosis. Liver transplantation (LT) has become an applicable treatment for a subset of these patients.

Conference:

Presenting Author: Rehman Z

Authors: Rehman Z, Ford S, Dasari B, Hughes S, El-Shafie M,

Keywords: metastases, transplant, liver, neuroendocrine,

#3792 Validation of a single time-point estimates of 177Lu-PRRT absorbed doses and impact on patient management for 192 therapies

Introduction: Dosimetry calculation after 177Lu-DOTA-TATE Peptide Receptor Radionuclide Therapy (PRRT) enables to estimate radiation doses absorbed by normal organs and target lesions. Previously, we described a newly developed model to predict absorbed doses (ADs) from a single post-treatment study with good accuracy as compared to the standard multiple time-points protocol.

Conference:

Presenting Author:

Authors: Chicheportiche A, Krausz Y, Godefroy J, Gross D, Grozinsky-Glasberg S,

Keywords: PRRT, Dosimetry, SPECT/CT, Single time-point,