Endocrine neoplasias and non-endocrine neoplasias associated with primary aldosteronism

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Introduction: Primary aldosteronism (PA) is the main cause of secondary arterial hypertension (AH) of endocrine origin (1). Clinical presentation may include resistance to treatment for AH, hypokalemia, with the autonomous secretion of aldosterone. Somatic mutations and epigenetic factors are the most frequent etiologies (2). Adrenal tumors may be a characteristic of MEN1 syndrome (3). Some case reports have associated endocrine neoplasms with PA; however, the real prevalence of this association is unknown (3).

Aim(s): To determine the prevalence of endocrine and non-endocrine neoplasms in a population ≥18 years old with the full confirmatory test for PA in the Hospital Universitario Fundación Santa Fe de Bogotá between 2009 to 2020.

Materials and methods: A retrospective observational study with patients diagnosed with PA, from January 2009-October 2020. Medical records, adrenal venous sampling, and pathology reports were analysed.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Huertas Gnecco B

Authors: Huertas Gnecco B, González Devia D, Jaramillo Chacón H, López Panqueva R, Cañón Solano D,

Keywords: primary hyperaldosteronism, primary aldosteronism, neuroendocrine tumor, endocrine tumor, neoplasia,