Genetic Features and Immunoprofile of Sporadic Well-Differentiated Neuroendocrine Tumors of Gastric


Introduction: Well-differentiated Type III gastric neuroendocrine tumors (gNET III) are histologically distinct subset that have a unique pathogenesis and clinical course.

Aim(s): To further evaluate the genetic, pathological, and clinical features of gNET III.

Materials and methods: We analyzed the expression of Ki67, SSTR2/5 in gNET III in relation to alterations in the PI3K-Akt pathway, TP53 status (p53/Rb immunohistochemistry) and ALT were detected (ATRX, DAXX). Fisher’s exact test and X2 was performed.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Ji Y

Authors: Xie Y, Xu Y, Zeng H, Wang H, Hou Y,

Keywords: genetic, wdnet.,

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