Hypoglycaemia in a Patient with Glucagonoma-Coincidence of a Glucagonoma and Insulinoma in a Patient with Multiple Endocrine Neoplasia Type I

#1063

Introduction: We report the case of a 54 year old female with a known MEN1 syndrome with primary Hyperparathyroidism, a Prolactinoma and a pancreatic tumor. The patient complains about episodes of fatigue and sweating, both symptoms improve immediately after a meal.

Aim(s): Lab tests show a fasting glucose of 45 mg/dl, (without hypoglycaemic symptoms). A MRI of the pancreas shows a tumor with typical radiologic characteristics of a pancreatic neuroendocrine Tumor (PNET) with an increasing diameter from 22 to 27 mm (compared to one year ago). Further lab tests show an elevated glucagon level with 942 pg/ml (- 250 pg/ml). Insulin and C-peptide values were in the lower normal range.

Materials and methods: Due to the clinical symptoms and the increase in tumor size a left sided pancreatectomy and splenectomy was performed.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Ploner F, Plank J, Humer-Fuchs U, Lax S, Noggler P,

Keywords: MEN1, Glucagonoma,

To read the full abstract, please log into your ENETS Member account.