Microscopic resection margin status does not predict long-term survival in small bowel neuroendocrine tumors

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Introduction: Small bowel neuroendocrine tumors (SBNETs) are increasing in incidence and are the most common small bowel malignancy. The characteristic nodal mass, which may extend high into the mesentery, can make achieving microscopically negative resection margins difficult without resecting excessive lengths of small bowel.

Aim(s): Determine the prognostic value of resection margin status and other markers of tumor biology in patients with SBNET.

Materials and methods: Records were reviewed for patients who had undergone resection for SBNET at a single centre between 1996 and 2019. Resection margin status and other key markers of tumor biology (e.g. T stage, Ki67, apical node status) were extracted from original pathology reports. The prognostic value of each pathology marker, in terms of overall (OS) and disease-free survival (DFS), was determined.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Mentor K, Ammar K, Thakkar R, Farrington E, Buckley E,

Keywords: small bowel, grading, resection margin, survival,