miR-29b serum levels are down-regulated in patients with neuroendocrine tumors

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Introduction: Due to its involvement in tumor biology as well as tumor-associated stroma cell responses, recent data suggested a potential role of miR-29 as a biomarker for different malignancies.

Aim(s): However, the role of miR-29 in neuroendocrine tumors (NETs) is only poorly understood.

Materials and methods: We analysed concentrations of circulating miR-29b in 45 patients with NET and compared them to 19 healthy controls. Results were correlated with clinical records.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Roderburg C

Authors: Özdirik B, Mohr R, Jann H, Geisler L, Tacke F,

Keywords: neuroendocrine tumor, miRNA, miR-29, prognosis, biomarker,