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Neuroendocrine Carcinoma of the Upper Urinary Tract: A Case Report


Introduction: There are no dedicated guidelines for treatment of urothelial NEC given disease rarity. An aggressive approach, including neoadjuvant cisplatin-based chemotherapy + nephroureterectomy and adjuvant platinum-based chemotherapy, is recommended.

Aim(s): We present the management of a patient with urothelial NEC.

Materials and methods: A 74-years-old female presented with weight loss and abdominal pain. CT scan showed a voluminous lesion close to the IVC, the duodenum and the right kidney with hydronephrosis; the lesion was closed to the right psoas muscle, the right common and external iliac arteries. A 18-FDG-PET scan showed intense uptake in the right para-renal region, whilst the PET-Gallium-68 was negative.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Rossi R

Authors: Rossi R, Monteleone M, Altomare M, Torchio M, Pusceddu S,

Keywords: Urothelial neuroendocrine carcinoma, chemotherapy, surgery, radiotherapy,

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