Pancreatic metastases in neuroendocrine neoplasia: A systematic review

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Introduction: Neuroendocrine neoplasias (NENs) are a heterogeneous group of neoplasms that often metastasise to distant organs, with the liver and bones as common targets. However, metastases to the pancreas are uncommon, accounting for 2–5% of pancreatic malignancies.

Aim(s): This systematic review aims to synthesise available evidence on the occurrence, clinical characteristics, diagnostic tools, and outcomes of patients with pancreatic metastases from NEN, providing a comprehensive overview to guide clinical decision-making.

Materials and methods: A systematic search was conducted in PubMed, Embase, and Cochrane Library databases. Eligible studies included those reporting clinical cases, diagnostic methods, and treatment outcomes of NETs with pancreatic metastasis. The search strategy incorporated terms related to "neuroendocrine tumours," "pancreatic metastases," "diagnosis," and "incidence." Studies were screened according to PRISMA guidelines.

Conference:

Presenting Author:

Authors: Rinzivillo M, Romano E, Dell' Unto E, Marasco M, Panzuto F,

Keywords: pancreatic metastasis, 68Gallium-PET, incidence,