Pancreatic proinsulinomas - Single-center experience

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Introduction: Proinsulinoma is an extremely rare pancreatic neuroendocrine tumor that produces hormone proinsulin. Symptomatic of these tumors is still unclear. There are insufficient data about them in the world literature.

Aim(s): To tell about our experience in description and surgical treatment of patients with proinsulinoma.

Materials and methods: Since 2017 10 patients with pancreatic proinsulinomas were treated in our department. The proinsulinoma diagnosis was established basing on the laboratory data: elevated proinsulin level with normal or subnormal insulin level and clinical hypoglycaemia. Most of patients (7) were young females with a median age 32.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Kaldarov A

Authors: Kaldarov A, Kriger A, Berelavichus S, Gorin D, Panteleev V,

Keywords: proinsulinoma, hypoglycaemia, neuroendocrine tumor, pancreas, insulinoma,