Predictors based on the radiologic characteristics for aggressiveness of small (＜20 mm) non-functioning pancreatic neuroendocrine tumours

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Introduction: The management of small non-functioning PNETs remains controversial due to their heterogeneity. Results from some retrospective surgical reports found that a subset of small NF-PNETs may show aggressive behaviour, for which surgical resection is recommended.

Aim(s): To find the association between preoperative Computed Tomography (CT) features combined with tumour marker and known high-risk factors of small non-functioning pancreatic neuroendocrine tumours (NF-PNETS), thereby selecting appropriate treatment strategy for these patients.

Materials and methods: 114 patients with NF-PNETs<20 mm who undergoing surgical operation were retrospectively analysed from 2009-2023. Univariate and multivariable logistic regression analyses were performed to find the relationship between preoperative clinical pathological and CT features and high-risk factors. The recurrence-free survival (RFS) rates with and without high-risk factors were compared.

Conference:

Presenting Author: Shu-Jie R

Authors: Ren S, Fan Y, Tan C, Wang X, Tan Q,

Keywords: small pancreatic neuroendocrine tumour, high-risk factor, radiologic characteristics, tumour marker, prognostic factor,