#3080
Impact of Multimodal Perioperative Treatment in Patients with Resected Non-Metastatic Grade 3 Neuroendocrine Neoplasms (NEN G3)
Introduction:
Patients with grade 3 neuroendocrine neoplasm (NEN G3) have a limited prognosis. Even in a non-metastatic stage, the risk of recurrence after surgery is high. Multimodal perioperative treatment, including chemotherapy and/or radiotherapy in an adjuvant or neoadjuvant setting, has improved the prognosis in numerous tumor entities; however, it has not been systematically evaluated in NEN G3 so far. Nevertheless, perioperative chemotherapy is generally recommended in most current treatment guidelines for NEN G3.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Authors:
Apostolidis L,
Starke H,
Bhatti I,
Jäger D,
Winkler E,
Keywords:
NEN G3,
neuroendocrine carcinoma,
adjuvant,
neoadjuvant,
surgery,
#3022
Diagnostic Accuracy of 68Gallium Positron Emission Tomography (68Ga PET), Endoscopic Ultrasound (EUS) and Computed Tomography in the Assessment of Lymphnode Metastases by Nonfunctioning Pancreatic Neuroendocrine Neoplasms
Introduction:
The presence of nodal metastasis is one of the most important predictive factors for recurrence after radical surgery for nonfunctioning Pancreatic Neuroendocrine Neoplasms (NF-PanNEN). Nevertheless, it is not clear which is the best diagnostic examination to identify preoperatively lymphnodal metastasis.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Giannone F
Authors:
Giannone F,
Muffatti F,
Partelli S,
Andreasi V,
Guarneri G,
Keywords:
imaging,
lymph node,
metastases,
#3007
An mRNA-based Classifier Identifies PanNETs with Different Clinicopathological Characteristics
Introduction:
Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of neoplasms that varies from indolent to highly aggressive diseases. Previous studies have suggested alterations of ATRX/DAXX as biomarkers of dismal prognosis, yet inconclusive data (especially in the metastatic setting) prevent those biomarkers to be used as routine clinical tests.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Authors:
Vicentini C,
Barbi S,
Bersani S,
Rusev B,
Lawlor R,
Keywords:
PanNET,
gene expression profile,
ATRX/DAXX mutations,
patients’ stratification.,