PRRT in Hindgut and Cancer of Unknown Primary NEN

#2290

Introduction: There are limited data regarding PRRT in hindgut and CUP (cancer of unknown primary).

Aim(s): To compare the long term effectiveness of PRRT (90Y or 177Lu DOTATATE), based on OS and PFS, in patients with extensive, progressive, non-resectable NEN hindgut and CUP origin.

Materials and methods: 22 patients, hindgut, n=8 and CUP n=14. All treated with PRRT; 177Lu (n=8); 90Y (n=14). Clinical responses were assessed 6 weeks after PRRT and then at the 3-month intervals. The clinical efficacy determine evaluating performance status (PS) and reduction of clinical symptoms. OS and PFS were assessed using Kaplan –Meier. Radiological response was classified according to RECIST 1.0.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Ćwikla J

Authors: Kolasińska-Ćwikła A, Lewczuk-Myślińska A, Cichocki A, Roszkowska-Purska K, Dobkowski P,

Keywords: NENs, PRRT, Hindgut, CUP,