Abstract Library

#4578 Dissecting the role of collagen quantitation via tissue-tethered digital analysis in small bowel neuroendocrine tumours and related mesenteric tumour deposits

Introduction: Small bowel neuroendocrine tumours (sb-NETs) and related mesenteric tumour deposits (MTDs) can present dense collagen and fibrosis. Despite well-known clinical consequences of this characteristic (bowel obstruction and ischemia), the relationship between SB-NETs and MTDs collagen deposition has been poorly evaluated.

Conference:

Presenting Author: Ali M

Authors: Ali M, Gambella A, Checchin F, Malerba D, Sambuceti V,

Keywords: neuroendocrine tumour, small intestine, collagen, fibrosis,

#4500 Effectiveness of palbociclib plus letrozole as first line therapy of metastatic breast neuroendocrine carcinoma: A case report

Introduction: Palbociclib plus endocrine therapy is the standard treatment of advanced luminal breast cancer. However, we lack data on its effectiveness in breast neuroendocrine carcinoma (NEC).

Conference:

Presenting Author:

Authors: Saidi M, Aris H, Elyebdri H, Ilham L,

Keywords: breast neuroendocrine carcinoma, CDK4/6 inhibitor, palbociclib, endocrine therapy,

#4492 Utility of NETest 2.0 as a biomarker for neuroendocrine tumours: The Swiss experience – Real-world data

Introduction: The NETest 2.0 is a PCR assay of circulating mRNA, scored 0-100. It has been developed as a biomarker to diagnose neuroendocrine neoplasia (NEN) and to provide tumour prognostic information.

Conference:

Presenting Author: Chirindel A

Authors: Chirindel A, Wild D, Voegeli M, de Dosso S, Siebenhüner A,

Keywords: NETest, tumour biomarker, NEN, disease presence, disease progression,

#4457 Primary mixed hepatocellular carcinoma-neuroendocrine carcinoma: A case report

Introduction: Mixed epithelial neoplasms (MiNENs) are characterised by the coexistence of neuroendocrine and non-neuroendocrine components within a single tumour, each discernible histologically and immunohistochemically, with a minimum tumour proportion of 30%. Primary hepatic MiNENs are exceedingly rare entities.

Conference:

Presenting Author: Tang Y

Authors: Wang Y, Wang R, Yi X, Guo M, Tang Y,

Keywords: pancreatic neuroendocrine tumour, functional, parathyroid hormone related peptide,

#4098 A case of functional pancreatic neuroendocrine tumor with hypercalcemia as the main manifestation

Introduction: NEN is a type of rare neoplasm originated from peptidenergic neurons and neuroendocrine cells. Even for functional neuroendocrine tumors, the hormones secreted can be temporally and spatially heterogeneous. Hypercalcemia being a rare clinical manifestation of F-pNEN.

Conference:

Presenting Author: Yingmei T

Authors: Yanping Z, Yingmei T, Jieting D,

Keywords: pancreatic neuroendocrine tumor, functional, parathyroid hormone related peptide,