Reassessment of Risk Factors Associated with Locoregional Lymph Nodal Metastases in Well-Differentiated Appendiceal Neuroendocrine Neoplasms


Introduction: To prevent loco-regional recurrence and subsequent development of distant metastases in Appendiceal Neuro-Endocrine Neoplasms (ANEN), the existing Guidelines have identified risk factors which would indicate a prophylactic right hemicolectomy(RHC).

Aim(s): To assess the importance of those factors and their association with regional lymph nodal invasion(LNI) at RHC.

Materials and methods: Over a 10-year period, 263 patients with ANEN were identified. Patients who underwent RHC were categorized into Group A(GA): those with LNI at RHC and Group B(GB): those without LNI. The original tumour size, location, margin invasion, grade, meso-appendiceal invasion (MAI), angioinvasion, lymph vessels and perineural invasion were assessed.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Galanopoulos M, Evans N, McFadyen R, Naik R, Drami I,

Keywords: appendix, neuroendocrine neoplasm, lymph node metastases, appendicectomy, right hemicolectomy,

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