Surgical Management of Neuroendocrine Tumor-Associated Liver Metastases


Introduction: Liver metastasis is common among patients who suffer from neuroendocrine tumors (NETs). Radical surgery is the standard treatment whenever possible but there is still controversies concerning the treatment strategies such as resection of the primary, role of debulking surgery, liver transplantation (LT) and neoadjuvant or adjuvant therapies.

Aim(s): Surgical resection remains to be the mainstay of treatment for NET. Radical resection of both the primary and NELM should be contemplated whenever possible. If the tumor load could be reduced by 80–90%, surgical debulking with or without the combination of ablation should still be considered.

Materials and methods: we report a case about man who has 69 old year with pancreatic neuroendocrin tomor and liver metastasis the patient is a smoker and an occasional drinker, known with type two diabetes mellitus (DM), receiving insulin therapy. He was diagnosed by contrast-enhanced computed tomography (CT) in January 2015 with a locally invasive pancreatic body mass, intraabdominal adenopathies and liver nodules, suggestive of metastases. Histopathological diagnosis was obtained through liver biopsy: neuroendocrine tumor with a 9% Ki67 proliferation index

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Bengueddach A, Boudjnene N, Derriche H, Kaid M, Tabeti B,

Keywords: surgery, pancreas, liver metastasis,

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